2:00PM Water Cooler 4/12/2023

By Lambert Strether of Corrente.

Bird Song of the Day

Canyon Towhee, San Juan Wash, south side of the Black Hills, Pima, Arizona, United States. “‘Complex song’, blending into normal song later in the cut, from a bird moving at mid-height in a dense bush.”

* * *


“So many of the social reactions that strike us as psychological are in fact a rational management of symbolic capital.” –Pierre Bourdieu, Classification Struggles


“Trump’s ability to get away with shooting somebody in the middle of 5th Ave is likely waning” [Boing Boing]. “Trump’s popularity is falling apart. While he might be able to win a Republican primary, it seems highly unlikely that the indicted fraudster, who is also on trial for rape, could win a general election. Never count the Orange Menace out, however, because Lindsay Graham and Don Jr are still pulling for him.”” • That’s the lead. Then again–

“Trump Leads DeSantis In Our 2024 Republican Primary Polling Average” [FiveThirtyEight]. “Today, FiveThirtyEight is launching our national polling average for the 2024 Republican presidential primary. It shows former President Donald Trump receiving 49.3 percent of the national vote and Florida Gov. Ron DeSantis (who has not officially entered the race) receiving 26.2 percent. Former Vice President Mike Pence, another potential candidate, is at 5.8 percent, while declared candidate and former UN Ambassador Nikki Haley is at 4.3 percent.”

“Trump says he’d “never drop out” of 2024 race, even if convicted” [Axios]. “Former President Trump made clear Tuesday evening he won’t drop out of the 2024 presidential race if convicted of charges related to a 2016 illegal hush money payment to adult film star Stormy Daniels. Fox News host Tucker Carlson asked Trump if there’s anything legal that could make the 2024 Republican presidential candidate drop out of the race. ‘No, I’d never drop out,’ Trump said. ‘That’s not my thing. I wouldn’t do it,’ he added.” • I should probably have gone to find a transcript, since Trump is very often misquoted. That said, IIRC the Daniels payment was not legal, but that doesn’t mean Trump did anything illegal.

“DA Alvin Bragg’s one-time rival explains why he was ‘100 percent right’ to leave a gaping hole in Trump’s indictment” [Insider]. “Bragg’s approach appears to be a deliberate strategy to choose among four different secondary crimes later on. A 30-year veteran of the DA’s office told Insider that Bragg will lay the specifics out in a so-called ‘bill of particulars’ down the road.” • So we weren’t looking at an indictment, but a meta-indictment; a piece of sandbagging. Correct me if I’m wrong here, but under our system of justice, doesn’t the defendant get a chance to prepare?

“Tim Scott is the most intriguing GOP presidential hopeful most Republicans haven’t heard of” [Insider]. “National attention is transfixed on former President Donald Trump and Florida Gov. Ron DeSantis. A protracted and ugly clash between the two men appears inevitable, even though DeSantis isn’t expected to announce until at least May. If the fallout scars both men, an opening could easily emerge for a third hopeful. South Carolina Sen. Tim Scott is strongly positioned to capitalize. Scott, like DeSantis, has yet to formally announce a campaign, though he established an exploratory committee on Wednesday. Scott could very well end up being the only GOP senator to enter the field after Sen. Tom Cotton demured, and neither Sens. Ted Cruz nor Marco Rubio seem likely to launch a second presidential run… Scott’s most compelling case might just be his campaign’s bank account. Having easily won reelection, he started the year with over $20 million at the ready. In comparison, Sen. Elizabeth Warren used $10.4 million to help seed her Democratic presidential run in 2019…. The South Carolinian is also well positioned if the Republican National Committee imposes grassroots donor thresholds for official primary debates. Axios reported in late January that the RNC is considering using the same tactic that Democrats used to winnow their debate field in 2019….” • Plus he’s Black, which would totally own the libs.

Democrats en Déshabillé

Patient readers, it seems that people are actually reading the back-dated post! But I have not updated it, and there are many updates. So I will have to do that. –lambert

I have moved my standing remarks on the Democrat Party (“the Democrat Party is a rotting corpse that can’t bury itself”) to a separate, back-dated post, to which I will periodically add material, summarizing the addition here in a “live” Water Cooler. (Hopefully, some Bourdieu.) It turns out that defining the Democrat Party is, in fact, a hard problem. I do think the paragraph that follows is on point all the way back to 2016, if not before:

The Democrat Party is the political expression of the class power of PMC, their base (lucidly explained by Thomas Frank in Listen, Liberal!). It follows that the Democrat Party is as “unreformable” as the PMC is unreformable; if the Democrat Party did not exist, the PMC would have to invent it. If the Democrat Party fails to govern, that’s because the PMC lacks the capability to govern. (“PMC” modulo “class expatriates,” of course.) Second, all the working parts of the Party reinforce each other. Leave aside characterizing the relationships between elements of the Party (ka-ching, but not entirely) those elements comprise a network — a Flex Net? An iron octagon? — of funders, vendors, apparatchiks, electeds, NGOs, and miscellaneous mercenaries, with assets in the press and the intelligence community.

Note, of course, that the class power of the PMC both expresses and is limited by other classes; oligarchs and American gentry (see ‘industrial model’ of Ferguson, Jorgensen, and Jie) and the working class spring to mind. Suck up, kick down.

* * *

CA: “Aspen Vacation Home of Dianne Feinstein and Her Late Husband Sells for $25.25 Million” [Wall Street Journal]. “The longtime Colorado vacation home of Sen. Dianne Feinstein and her late husband, Richard C. Blum, has sold for $25.25 million, according to property records…. Mr. Blum, founder of the San Francisco-based investment firm Blum Capital Partners, and Mrs. Feinstein married in 1980, when she was mayor of San Francisco. A trust led by Mr. Blum paid $1.975 million for the Aspen-area land in 1996, records show, and the home was completed in 1998. The couple hosted events, foreign-policy experts and others at Bear Paw Ranch over the years. Mr. Blum was a longtime skier with a strong interest in Tibetan Buddhism, and filled the home with Tibetan and Nepali Buddhist artifacts.”

TN: “Reinstated Tennessee lawmaker Justin Jones says he’ll continue to call for gun reform” [CNN]. “After being sworn back into the Tennessee House of Representatives, a lawmaker who was expelled just days ago over a gun control demonstration on the chamber floor said he’ll continue to call for gun reform. ‘The first thing I do when I walk into this building as a representative is to continue that call for commonsense gun legislationlicensing guns, like cars? With “Gun Ed,” like cars?

TN: “Justin Pearson and Justin Jones Have a History of Breaking the Status Quo, Even With Clothing” [Vogue]. “But in many ways Jones and Pearson were already bucking against the so-called status quo of the Republican-controlled chambers—in part through their sartorial choices, which have included Afros, pristine white suits, and dashikis (a colorful patterned garment, which originated in West Africa, for both formal and informal occasions). If President Barack Obama became a target of Republican-led attacks and vitriol by donning a tan suit, imagine the chatter a white one would have elicited? Or a dashiki?…. Jones, who is of Filipino and Black descent, delivered a nearly 20-minute defense before the vote took place, calling the affair a “lynch mob assembled—to not lynch me but our democratic process.” He immediately stood out in the sea of drab-colored suits and closely cropped haircuts through his white suit, hoop earring, and long curls that were loosely pulled back into a ponytail. Ditto Pearson. The 29-year-old lawmaker has a big, combed-out Afro and wore a black-and-white dashiki over his crisp white button-down and tie, with a navy blazer worn over the ensemble. Here were two men of color tinkering with the standard politician’s uniform and transforming it into something decidedly more personal and attuned to who they are. It felt even more poignant that it was taking place while being ousted from the very space they were attempting to change.” • Hmm.

Realignment and Legitimacy

“See the fastest growing (and shrinking) U.S. states” [Axios]. “Idaho, Montana and Florida saw the highest population growth among U.S. states between 2020-2022, per new U.S. Census Bureau data, while New York, Illinois and Louisiana suffered the most shrinkage. The past few years have been especially turbulent for population trends, with the COVID-19 pandemic affecting birth and death rates, interstate and international migration, and more…. Some of the fastest growing areas — we’re looking at you, Arizona, Nevada and New Mexico — are also some of the most vulnerable to the ongoing effects of climate change, like drought and a dwindling water supply. The bottom line: It’ll take a few more years for the effects of the pandemic to fully shake out, but there’s never been a more fascinating time to look at data like this.” • Handy map:


“I am in earnest — I will not equivocate — I will not excuse — I will not retreat a single inch — AND I WILL BE HEARD.” –William Lloyd Garrison

Resources, United States (National): Transmission (CDC); Wastewater (CDC, Biobot; includes many counties); Variants (CDC; Walgreens); “Iowa COVID-19 Tracker” (in IA, but national data).

Lambert here: Readers, thanks for the collective effort. We are now up to 50/50 states (100%). This is really great! (It occurs to me that there are uses to which this data might be put, beyond helping people with “personal risk assessments” appropriate to their state. For example, thinking pessimistically, we might maintain the list and see which states go dark and when. We might also tabulate the properties of each site and look for differences and commonalities, for example the use of GIS (an exercise in Federalism). I do not that CA remains a little sketchy; it feels a little odd that there’s no statewide site, but I’ve never been able to find one. Also, my working assumption was that each state would have one site. That’s turned out not to be true; see e.g. ID. Trivially, it means I need to punctuate this list properly. Less trivially, there may be more local sites that should be added. NY city in NY state springs to mind, but I’m sure there are others. FL also springs to mind as a special case, because DeSantis will most probably be a Presidental candidate, and IIRC there was some foofra about their state dashboard. Thanks again!

Resources, United States (Local): AK (dashboard); AL (dashboard); AR (dashboard); AZ (dashboard); CA (dashboard; Marin); CO (dashboard; wastewater); CT (dashboard); DE (dashboard); FL (wastewater); GA (wastewater); HI (dashboard); IA (wastewater reports); ID (dashboard, Boise; dashboard, wastewater, Central Idaho; wastewater, Coeur d’Alene; dashboard, Spokane County); IL (wastewater); IN (dashboard); KS (dashboard; wastewater, Lawrence); KY (dashboard, Louisville); LA (dashboard); MA (wastewater); MD (dashboard); ME (dashboard); MI (wastewater; wastewater); MN (dashboard); MO (wastewater); MS (dashboard); MT (dashboard); NC (dashboard); ND (dashboard; wastewater); NE (dashboard); NH (wastewater); NJ (dashboard); NM (dashboard); NV (dashboard; wastewater, Southern NV); NY (dashboard); OH (dashboard); OK (dashboard); OR (dashboard); PA (dashboard); RI (dashboard); SC (dashboard); SD (dashboard); TN (dashboard); TX (dashboard); UT (wastewater); VA (dashboard); VT (dashboard); WA (dashboard; dashboard); WI (wastewater); WV (wastewater); WY (wastewater).

Resources, Canada (National): Wastewater (Government of Canada).

Resources, Canada (Provincial): ON (wastewater); QC (les eaux usées); BC, Vancouver (wastewater).

Hat tips to helpful readers: Art_DogCT, B24S, CanCyn, ChiGal, Chuck L, Festoonic, FM, FreeMarketApologist (4), Gumbo, hop2it, JB, JEHR, JF, JL Joe, John, JM (9), JW, KatieBird, LL, Michael King, KF, LaRuse, mrsyk, MT, otisyves, Petal (5), RK (2), RL, RM, Rod, square coats (11), tennesseewaltzer, Utah, Bob White (3).

* * *


On nasal vaccines:


“SARS-CoV-2 infection weakens immune-cell response to vaccination” [NIH]. “The researchers found that vaccination of people who had never been infected with SARS-CoV-2 induced robust CD4+ and CD8+ T-cell responses to the virus’ spike protein. In addition, these T cells produced multiple types of cell-signaling molecules called cytokines, which recruit other immune cells—including antibody-producing B cells—to fight pathogens. However, people who had been infected with SARS-CoV-2 prior to vaccination produced spike-specific CD8+ T cells at considerably lower levels—and with less functionality—than vaccinated people who had never been infected. Moreover, the researchers observed substantially lower levels of spike-specific CD8+ T cells in unvaccinated people with COVID-19 than in vaccinated people who had never been infected. Taken together, the investigators write, these findings suggest that SARS-CoV-2 infection damages the CD8+ T cell response, an effect akin to that observed in earlier studies showing long-term damage to the immune system after infection with viruses such as hepatitis C or HIV. The new findings highlight the need to develop vaccination strategies to specifically boost antiviral CD8+ T cell responses in people previously infected with SARS-CoV-2, the researchers conclude.” • I am not knowledgeable enough to say that this means “Leonardi was right about T cells.” Perhaps readers more expert than I can comment.

“Going long: Viruses linger with lasting impact” [Fred Hutch Cancer Center]. “NIH scientists are currently examining the similarities between long COVID and other post-viral fatigue ailments such as long-neglected ME/CFS. Fred Hutch infectious disease expert Steve Pergam, MD, MPH, called the long-term consequences of infections ‘a really intriguing space.’ ‘I would argue that it’s not just viruses,’ he said, pointing to a recent review of unexplained post-acute infection syndromes by Yale immunologist Akiko Iwasaki, PhD, and colleagues. Published in the journal Nature, the authors said (emphasis added), ‘the relatively similar symptom profiles of individual post-acute infection syndromes, irrespective of the infectious agent, as well as the overlap of clinical features with ME/CFS, suggest the potential involvement of a common etiopathogenesis.’ In other words, it’s not just COVID that goes long. ‘It may be a number of different pathways to infection in general that can lead to chronic complications,’ Pergam said. ‘A classic example is something like the gastrointestinal bacteria campylobacter which has been associated with rheumatologic problems. These infections can set off a pathway toward autoimmunity and other complications. It depends on the illness and the severity of the illness on whether it lingers or there’s ongoing issues.’ Some of it, Pergam said, is related to our immunity and how we respond to organisms. And some of it is the pathogen itself.”

Origins Debate

“Congressional memo: Virologists drafted article against the lab leak theory on behalf of Wellcome Trust, NIH” [US Right to Know]. “A March 2020 paper in Nature Medicine titled ‘The proximal origin of SARS-CoV-2‘ assured the public that the virus’ genome demonstrated an origin in wildlife. Hundreds of news organizations cited the article to assert that the lab leak theory was a ‘conspiracy theory.’ But the new congressional memo shows that the lead author of the article told the scientific journal that the writing had been “prompted” by then-Wellcome Trust Director Jeremy Farrar, leader of NIH’s National Institute of Allergy and Infectious Diseases Anthony Fauci, and NIH Director Francis Collins. The virologists met with Farrar, Fauci and Collins in a private teleconference on February 1, 2020, emails released under the Freedom of Information Act have shown — a meeting some scientists have criticized as improper. ‘There has been a lot of speculation, fear mongering, and conspiracies put forward in this space,’ acknowledged lead author Kristian Andersen in a February 12 email, according to the new memo.” And: ‘The involvement of Collins, Fauci and Farrar in the article was not disclosed until it was made apparent in a Freedom of Information Act lawsuit in June 2021, 15 months after the article had first made its enormous impact. The virologists have given shifting explanations of the purpose of the article, the new memo also shows. When hoping to demonstrate their integrity to the journal, Andersen said discussion of the evidence had been ‘agnostic.’ However when speaking to gain-of-function virologists who did not want to give credence to the possibility of a lab origin at all, the authors assured them that their purpose was to demonstrate the lab leak theory was outlandish from the jump.” • The problem I have here is that “The wicked flee when no man pursueth” (Proverbs 28:1). Guilty behavior is not guilt; if I were these guys, I’d want to slam the door too, regardless of (Yes, we already know virology funding is a cesspit; see Vanity Fair, of all places. But that tells us nothing of origins.)

Elite Malfeasance

Disinformation (1):

A long thread full of useful links, for those who need ammo.

Disinformation (2):

Hospital Infection Control is at it again:

* * *

Looks like “leveling off to a high plateau” across the board. (I still think “Something Awful” is coming, however. I mean, besides what we already know about.) Stay safe out there!

Case Data

NOT UPDATED BioBot wastewater data from April 10:

For now, I’m going to use this national wastewater data as the best proxy for case data (ignoring the clinical case data portion of this chart, which in my view “goes bad” after March 2022, for reasons as yet unexplained). At least we can spot trends, and compare current levels to equivalent past levels.

Covid Emergency Room Visits

From CDC NCIRD Surveillance, from April 8:

NOTE “Charts and data provided by CDC, updates Wednesday by 8am. For the past year, using a rolling 52-week period.” So not the entire pandemic, FFS (the implicit message here being that Covid is “just like the flu,” which is why the seasonal “rolling 52-week period” is appropriate for bothMR SUBLIMINAL I hate these people so much. Anyhow, I added a grey “Fauci line” just to show that Covid wasn’t “over” when they started saying it was, and it’s not over now. Notice also that this chart shows, at least for its time period, that Covid is not seasonal, even though CDC is trying to get us to believe that it is, presumably so they can piggyback on the existing institutional apparatus for injections.


NOT UPDATED From the Walgreen’s test positivity tracker, published April 11:

-1.8%. Below the low point of the previous valley.

Lambert here: Walgreens always updates. If they’re shutting it down, I’ll be disappointed…


Death rate (Our World in Data):

Total: 1,157,194 – 1,157,022 = 172 (172 * 365 = 62,780 deaths per year, today’s YouGenicist™ number for “living with” Covid (quite a bit higher than the minimizers would like, though they can talk themselves into anything. If the YouGenicist™ metric keeps chugging along like this, I may just have to decide this is what the powers-that-be consider “mission accomplished” for this particular tranche of death and disease).

Lambert here: 172 again. I hate that.

Excess Deaths

NOT UPDATED Excess deaths (The Economist), published April 2:

Lambert here: Big jump from the last reading in the “Central Estimate.”

Lambert here: Based on a machine-learning model. Looks like a data issue, to me. I”m not sure how often this updates, and if it doesn’t, I’ll remove it. (The CDC has an excess estimate too, but since it ran forever with a massive typo in the Legend, I figured nobody was really looking at it, so I got rid it.

• “COVID-19 a leading cause of death in children and young people in the US” [Imperial College London]. “Analysis of US health data highlights COVID-19 was a leading cause of death in children and young people, ranking 8th overall. COVID-19 was the underlying cause of death for more than 940,000 people in the US, including over 1,300 deaths among children and young people aged 0–19 years. These are the findings of a new study, led by researchers at the University of Oxford, and including researchers from the Department of Mathematics and MRC Centre for Global Infectious Disease Analysis at Imperial College London, which published in the journal JAMA Network Open.” •

Stats Watch

Inflation: “United States Consumer Price Index (CPI)” [Trading Economics]. “The consumer price index in the United States rose 5.0 percent from a year earlier to 301.836 points in March 2023, easing from a 6.0 percent advance the month before and missing market expectations forecasts of a 5.2 percent increase to 302.254 points. The headline inflation eased for a ninth consecutive month to the lowest level since May 2021, led by a sharp decline in the cost of energy.”

* * *

Tech: “Twitter Inc. ‘No Longer Exists’ As Elon Musk Inches Closer To X ‘Everything App’ Ambitions” [Forbes]. “Twitter Inc. ‘no longer exists’ and the company is now a part of X Corp., according to an April 4 filing in California federal court. Musk pointed to the fairly obscurely located filing in an early Tuesday tweet, which simply read, ‘X.’ …. Musk has indicated he hopes to transform Twitter/X into a wide-ranging service akin to China’s WeChat, telling a Morgan Stanley conference last month he wants his app ‘to become the biggest financial institution in the world.’ Musk said at the time he wanted X to become a peer-to-peer mobile payment platform where users can earn interest on their cash like at a bank, previously suggesting he wants his app to include a glut of services including ride-hailing and food delivery.” • I can say with confidence that we at NC would be happy to see a competitor to PayPal, even if this is a little self-serving.

The Bezzle: “Bitcoin Rally Continues, Gaining More Than 80% This Year” [New York Times]. • Maybe I have to recategorize Bitcoin. After all, there’s always a market for fraud.

The Bezzle: “Hey look, unicorns are rare again!” [TechCrunch]. “Investors are no longer minting nearly two unicorns per day. In fact, we’re down to barely more than one new mythical horned horse per week. Welcome to the new venture normal, where it seems stories of previously well-funded startups imploding will be more common than news of mega-rounds…. Declining valuations at tech companies big and small and the dearth of capital are together creating a parched startup landscape.” • That’s a damn shame.

* * *

Today’s Fear & Greed Index: 65 Greed (previous close: 59 Greed) [CNN]. One week ago: 55 (Neutral). (0 is Extreme Fear; 100 is Extreme Greed). Last updated Apr 12 at 1:52 PM ET.

Police State Watch

“New York’s mayor wants you to know how much he loves police robots [TechCrunch]. • Kill them with fire.l

Class Warfare

“Southern California ports reopen. Shutdown highlights high-stakes contract talks” [Los Angeles Times]. “Southern California dockworkers returned to the job Friday night, ending an approximately 24-hour shutdown at the Los Angeles and Long Beach ports — a crucial entry point for imports arriving from Asia. The temporary closure has exacerbated fears about a logistics infrastructure that has never fully recalibrated since the COVID-19 pandemic delays and has shone a stark, national spotlight on the high-stakes labor negotiations playing out at the ports. ‘This is quite clearly a wake-up call to the ports’ operators,’ said Harley Shaiken, a professor emeritus at UC Berkeley who specializes in labor issues. ‘This process hasn’t just been slow, it’s been inching along with very high stakes in the balance. ‘Because their members can shut down ports all along the West Coast, Shaiken said, the longshore union has unequaled power.'” • Moar robots!

“The actor, the hairstylist and the eye surgeon: Drugs and death in a Malibu beach house” [Los Angeles Times].

News of the Wired

Dang. Not wired again!

* * *

Contact information for plants: Readers, feel free to contact me at lambert [UNDERSCORE] strether [DOT] corrente [AT] yahoo [DOT] com, to (a) find out how to send me a check if you are allergic to PayPal and (b) to find out how to send me images of plants. Vegetables are fine! Fungi and coral are deemed to be honorary plants! If you want your handle to appear as a credit, please place it at the start of your mail in parentheses: (thus). Otherwise, I will anonymize by using your initials. See the previous Water Cooler (with plant) here. From MR:

MR writes: “Wildflowers planted from a can by someone with a green thumb (summer 2022).” More like this please!

* * *

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About Lambert Strether

Readers, I have had a correspondent characterize my views as realistic cynical. Let me briefly explain them. I believe in universal programs that provide concrete material benefits, especially to the working class. Medicare for All is the prime example, but tuition-free college and a Post Office Bank also fall under this heading. So do a Jobs Guarantee and a Debt Jubilee. Clearly, neither liberal Democrats nor conservative Republicans can deliver on such programs, because the two are different flavors of neoliberalism (“Because markets”). I don’t much care about the “ism” that delivers the benefits, although whichever one does have to put common humanity first, as opposed to markets. Could be a second FDR saving capitalism, democratic socialism leashing and collaring it, or communism razing it. I don’t much care, as long as the benefits are delivered. To me, the key issue — and this is why Medicare for All is always first with me — is the tens of thousands of excess “deaths from despair,” as described by the Case-Deaton study, and other recent studies. That enormous body count makes Medicare for All, at the very least, a moral and strategic imperative. And that level of suffering and organic damage makes the concerns of identity politics — even the worthy fight to help the refugees Bush, Obama, and Clinton’s wars created — bright shiny objects by comparison. Hence my frustration with the news flow — currently in my view the swirling intersection of two, separate Shock Doctrine campaigns, one by the Administration, and the other by out-of-power liberals and their allies in the State and in the press — a news flow that constantly forces me to focus on matters that I regard as of secondary importance to the excess deaths. What kind of political economy is it that halts or even reverses the increases in life expectancy that civilized societies have achieved? I am also very hopeful that the continuing destruction of both party establishments will open the space for voices supporting programs similar to those I have listed; let’s call such voices “the left.” Volatility creates opportunity, especially if the Democrat establishment, which puts markets first and opposes all such programs, isn’t allowed to get back into the saddle. Eyes on the prize! I love the tactical level, and secretly love even the horse race, since I’ve been blogging about it daily for fourteen years, but everything I write has this perspective at the back of it.


  1. Wukchumni

    Nations are not ruined by one act of violence, but gradually and in an almost imperceptible manner by the depreciation of their circulating currency, through its excessive quantity.


    1. bdy

      His picture of inflation is in keeping with his opinion that the Sun was the center of the universe. Observant, but blindered by the terms of the paradigm each purports to oppose.

  2. Jeff Stantz

    Regarding: ““SARS-CoV-2 infection weakens immune-cell response to vaccination””

    Anyone know what this means? Does it mean zinc may help with T Cells dysfunction?

    Regulatory Role of Zinc in Immune Cell Signaling

    Zinc has been shown to play a critical role in regulation of Lck activity. Lck associates with the cytoplasmic tail of the CD4 and CD8 coreceptors and upon TCR stimulation they bind to invariant regions of MHC molecules stabilizing the interaction between TCR and MHC-peptide.

  3. Fred

    Thanks for the nationwide population link About once a week I see an article about how California is losing population. Now I can respond with something that says we are not the only ones.

    1. petal

      The NY map is fascinating(western, Finger Lakes, and Plattsburgh area), matching up with what I’ve heard through the grapevine and friends leaving. Same with northern MI. Brother moved up to NW MI last year from southeastern MI, and NH is having a major housing crunch from out of staters showing up.

    2. Mark Gisleson

      I couldn’t help but wonder whether the areas emptying might be the most valuable after the oceans rise…

      1. Pat

        I couldn’t help but look at Florida and wonder if those moving there have heard how much of it is expected to be underwater over the next few decades.

        1. Carolinian

          They will “bounce back” to Upstate SC (green with a black dot). At 800 ft asl we will probably only drown due to water from the sky (there’s lots lately).

        2. Mark Gisleson

          I suspect a survey of new Florida residents would find them scoring below average on climate awareness. I also suspect a survey of Florida expatriates would show a higher than average awareness of climate change and rising sealevels.

          1. JTMcPhee

            I’m about to turn 77, here in FL. My house, per Google earth, is 18.2 feet asl. I read that ocean rise in the Gulf is about a centimeter a year. Not worrying, myself or my wife. Except for a Cat 3 or worsen storm coming up the Gulf coast and ramming into Tampa Bay, when the NOAA models show us clinging to the roof. Our grandkids, one set is planning to move to Tennessee in 8-10 years, which now looks to be square in the new Tornado Alley. The other is what, me worry? They are both smarter than that. We are all immortal, until we’re not…

          2. Daryl

            I recently moved away from Texas and while climate was not the only motivator, I will not miss the worsening regular 100+ temps and hurricanes.

    3. Mangelwurtzel

      I was briefly heartened to see that Hampshire County, Massachusetts was in the highest category of growth, defying all reason, until I realized it was probably all due to the (privatized) ongoing UMass dorm construction frenzy in Amherst. The latest iteration looks like an aircraft carrier rendered in Minecraft, but somehow uglier.

    4. The Rev Kev

      The only pity about that article is that it does not talk about the sort of people that are moving and why. Are they white flight from places like LA? Conservatives? Professionals. Do the different growth regions have different sorts of people moving there?

      1. FreeMarketApologist

        Given that it’s 2020-2022, prime ‘get out of Dodge’ time for NYC, the rise in the reasonably adjacent counties (that little green band to the north and west), was everybody moving to a cheaper area than the close-in sububrbs, and the eastern Hudson Valley, which was mostly already all filled up and pricey. (certainly saw the effects of that in my county).

      2. Tom Doak

        No, I believe the main reason behind some of these moving trends is not climate, but state income taxes.

        Florida, Texas, Tennessee, and Jackson Hole WY are growing madly, and wealth is fleeing California and NY ever since Trump and the Republicans limited the “state and local income tax” deduction, forcing rich people in blue states with high income taxes to pay up. They don’t want to pay up.

        I know this because they all want to join a great golf course in Florida and Texas when they move, and the prices of those have tripled, and people are building new courses to service all the tax refugees.

  4. Carolinian

    Re Boing Boing and, this morning, Salon–so Trump is collapsing just because they say so? Quick glance at latest Five Thirty Eight says Trump and Biden are 2024 even with Biden facing many negatives (the war, the economy) and Trump just having received his.


    Instead of ranting and raving perhaps these Dem sites should ask why that is. Biden is their Kool-Aid.

    1. Dr. John Carpenter

      Seems to me we’ve heard Trump was collapsing about as often as we’ve heard “the walls are closing in.”

    2. Katniss Everdeen

      While he might be able to win a Republican primary, it seems highly unlikely that the indicted fraudster, who is also on trial for rape, could win a general election

      Wait, Trump is on trial for rape?

      How did I miss that?

      1. bdy

        Not exactly but pretty much. Being sued for defamation when he denied a rape allegation, and for battery when the alleged rape happened. E Jean Carroll, ‘95-ish in a Bergdorf’s.

        Let’s not forget this guy partied with the Clintons ;)

        1. Pat

          Having shopped at Bergdorfs in that period, and having been around Trump trying to pick up women near that time, I find Carroll’s story to be…well the best I can say is unlikely.

          They got rid of the statute of limitations for sexual assault cases for a year, otherwise it would have only been defamation about denying and saying it was all to sell a book.

          1. The Rev Kev

            I thought that I read that Bragg had made his reputation by suing Trump over 100 times and that is what he campaigned on. That strikes me as a bias element.

  5. Objective Ace

    The researchers found that vaccination of people who had never been infected with SARS-CoV-2 induced robust CD4+ and CD8+ T-cell responses to the virus’ spike protein. In addition, these T cells produced multiple types of cell-signaling molecules called cytokines, which recruit other immune cells—including antibody-producing B cells—to fight pathogens. However, people who had been infected with SARS-CoV-2 prior to vaccination produced spike-specific CD8+ T cells at considerably lower levels—and with less functionality—than vaccinated people who had never been infected

    Like Lambert, I too am not knowledgeable enough to draw sweeping conclusions. But it occurs to me, that much of long covid has been speculated to be related cytokine storms–where the body releases too many cytokines into the blood too quickly. Given that, its not at all clear to me that the “robust” response seen in those vaccinated prior to covid is preferrable to the reduced response seen in those who were not vaccinated. That’s merely a hypothesis on my part–I’m not at all convinced of it. But I think more investigation is warranted.

    1. will rodgers horse

      here is a thought: people who got covid early on before the vaccine was available were already different in non random ways than those who did not.
      Leonardi fails to understand the limitations of observational trials over and over again.

    2. Basil Pesto

      But it occurs to me, that much of long covid has been speculated to be related cytokine storms–where the body releases too many cytokines into the blood too quickly.

      That’s not accurate to the best of my knowledge, and I think the ‘Cytokine Storm’ meme has always been a bit of a red herring. See eg Dr Satoshi Akima on the subject

    1. Jason Boxman

      An example of conservatives exercising political power. And an effective response for once.

      Liberal Democrats only exercise power against the left, such as it is.

  6. Pat

    I think Boing Boing is imbibing koolaid left over from 2016 when everyone knew Trump wouldn’t win.

    So his one time rival thinks Bragg is going to play whack a mole, “ if this doesn’t work, let me amend my indictment to that” or a friendly judge or both. Depending on Trump’s lawyers this could be brilliant. Bragg will just wear every one down and the judge can ignore the gaping holes on try two. OR is it possible that opponent just doesn’t want to admit that the DA’s office where he spent 30 years is now being run by this doofus, and Bragg couldn’t get more than what we have seen so far.

    1. square coats

      That Barnes guy they have on the Duran sometimes said that this gaping hole thing might be a reason to dismiss the case because the jury needs to be told what crimes they’re considering and how those crimes are to be considered, so if the alleged crime is a moving target then the judge can’t properly instruct the jury.

  7. Mikerw0

    Re: the map with population shifts…

    Look at the changes on the CAT exposed FL coastline. Right now the property insurance market is in crisis and not functioning in FL (and any CAT exposed coastline for that matter). All I have to say to them is good luck come hurricane season.

  8. Wukchumni

    “Aspen Vacation Home of Dianne Feinstein and Her Late Husband Sells for $25.25 Million” [Wall Street Journal]. “The longtime Colorado vacation home of Sen. Dianne Feinstein and her late husband, Richard C. Blum, has sold for $25.25 million, according to property records…

    I was blown away by the rather ostentatious displays of wealth I saw in Vail & Beaver Creek resorts, with the latter being the ne plus ultra of see me-dig me resorts, but then again i’ve never been to Aspen, how could they up the glitz factor of a Ritz-Carlton at the bottom of one of the chairs @ Beaver Creek?

    If you’re just a skier or boarder and not contemplating the purchase of a $25 million pad, a 5 day pass was $450, not exactly breaking the bank there, although that amount exceeds 1/3rd of Americans net worth, your penury way vary.

    You hear different languages on the slopes and in the restaurants and whatnot at resorts-not too dissimilar to what I experience here, but it remains a pretty lily white affair, skid row.

    1. Carolinian

      I was in Aspen once. They had Saab police cars instead of the lowly Crown-Vics. The poor cops probably couldn’t find a doughnut if they tried.

  9. ambrit

    “Correct me if I’m wrong here, but under our system of justice, doesn’t the defendant get a chance to prepare?”
    The answer to that is yes, until your money runs out. So, Trump will have to prepare for all four ‘possible’ charges. As far as I know, he cannot counter sue for “loss of income pursuant to a judicial fraud.” So, the extra money thrown at the wall, “just in case,” is a part of doing monkey business in these here United States of America.
    [A reply to your question about the “foreign gentlemen” follows yesterday’s query in the Water Cooler Comments.]

    1. JBird4049

      The important phrase here is “our system of justice.” It has become “their system of justice” with justice or rights being what they say it is.

      1. JBird4049

        It is a credit to this reality that my first thought reading this was not of The Onion was secondly with “that’s a bit much” jumbled up with “really, how interesting” being first. I am now thinking that with The Collapse only just really gaining strength, we might yet see The Onion go out of business.

    1. anon in so cal

      Love them, too, but only see them and the Abert’s near the desert. We have California and Spotted (previously Rufous-sided) here in LA. This time of year, there is a twice daily C Towhee “symphony,” when they make their little, sort of metallic, sound, at dawn and dusk.

  10. Dida

    Lambert, you missed the ‘breaking news’: Hersh revealed on Substack early this morning that Zelensky embezzled $400 million sent to Ukraine for the purchase of fuel. https://seymourhersh.substack.com/p/trading-with-the-enemy

    Hersh published this gem 10 hr ago and for the moment it’s making the rounds in the alternative media, with RT chiming in 4 hr ago. Tass also joined in the fun 2 hrs ago.

    1. square coats

      Thanks! I’ve been wondering just that! Interesting to see PBS, CNN, and Fox all on that list..

    1. flora

      adding: I’m really starting to wonder if there’s a big food monopoly war on independents and/or competitors.

      1. Geo

        Theory that I heard and makes the most sense is decades of under-investment in maintenance and upkeep due to basic greed is the reason. There’s only so long one can push these things off before things start to crumble (or explode)

      2. Randall Flagg

        You can be forgiven for thinking that.
        What is more necessary to human existence than food, water and clean air? If you and a few others have a monopoly on food…
        And/or the seeds to grow food.
        And/or the
        processing facilities.

  11. ChrisFromGA

    Over There
    Sing to the tune of, “Over there” by George M. Cohan

    Vitaly, get your gun
    Get your gun, get your gun
    Take it on the run
    On the run, on the run

    Hear them calling, you not me
    Every son of suzerainty
    Hurry right away
    No delay, die today

    Make your Uncle glad
    To have sacrificed to piss off Vlad
    Tell your sweetheart not to pine
    To be proud her boy’s in line

    Over there! Over there!
    Send the Kurds, Send the Slavs, over there
    You see the Yanks aren’t coming;
    From the fight they’re running,
    Though, The printer drums are humming everywhere!

    So prepare, say a prayer
    Send the Kurds, mongrel herds, to fight the bear
    We’ll not be over, we’re waxing our Range Rovers
    And we won’t do Jack till it’s over, over there

  12. JBird4049

    >>> “COVID-19 a leading cause of death in children and young people in the US…
    …”COVID-19 was the underlying cause of death for more than 940,000 people in the US, including over 1,300 deaths among children and young people aged 0–19 years. “

    Oh f*ck me. All in just one year according to the article. So, during our during our extremely and vitally important jihad against the Evil Ones on the other whateverside continues, we lost almost twice as many Americans as we lost in the Vietnam War.

    I remember the protests during the AIDS epidemic, but now?

    Nice to see that our priorities are right. Why, yes, yes I am being sarcastic.

  13. Geo

    Alternative to PayPal: Have you looked into Venmo? Most people I work with have switched to it and very few use PayPal now. Found it to be quite useful too. Not sure if it has any drawbacks for your needs though.

  14. Acacia

    Lambert, it looks like the tweet under “On nasal vaccines” is duplicated by “Disinformation (2)”, and the first one went AWOL.

  15. Richard

    A little question for Lambert; could you explain more on the concept of “words working too hard”? I am preparing a class on US corp. media propaganda, and I’ve identified 3 tells for paid, dishonest speech. One is the “wandering we”, when the second person is involved in a very loose way to make every listener believe there are common interests and agreed on facts. The wandering we shifts across a lot of subtext premises. The second tell is missing agency or the passive voice. The third tell is words “working too hard”. What I have for that so far is exaggeration and understatement, words working either to exaggerate some supposed positive effort, or working to understate our mountains of corruption. Can you add anything to my idea of “words working too hard”?

    1. Yves Smith

      I hope Lambert will pipe up.

      I can come up with one, “conversation”. This has come to have authoritarian overtones, as in a fake discussion between equals when either the relationship between the parties or the institutional dynamics mean the ability of aggrieved or merely mildly dissenting parties to state their views will be severely circumscribed.

      1. Richard

        Thanks Yves! I thought I was commenting in a Saturday w.c., but oops wrong day. Thanks for your help; I’ll ask Lambert again next week as well.

Comments are closed.