Author Archives: KLG

Coffee Break: More on American Science, Thomas Jefferson and AI, and Natural History for the Ages

Part the First: Beware of Resting on the Shoulders of Atlas.  Dr. Scott Atlas is a radiologist who is now ensconced in the Hoover Institution on War, Revolution, and Peace at Stanford (naturally, and in the tower, no less).  One can only surmise from the general run of their work product that (true) Revolution and […]

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Coffee Break: Apathetic Americans, Science Agonistes, and Cool Science

Part the First: Jessica Wildfire on Apathetic Americans.  As a paid-up member of the Professional Managerial Class who came from a thoroughly working-class background, I tend to hear and see things differently from most of my colleagues.  An enduring theme among them is “They just don’t seem to care…”  Not exactly.  From Heads Above Water: […]

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Progress in Understanding Early-Onset Cancers?

Cancer has been recognized as an environmental disease since the first description of chimney sweep’s cancer by Percivall Pott in 1775.  The primary social determinant of this disease is described well in this article Lancet Oncology (Abstract then unfortunately a paywall), even if the “social determinants of health” are anathema during our MAHA Moment.  More […]

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Coffee Break: Against AI, Stem Cells, Cancer Chemotherapy, A Note on Louis Pasteur

Part the First: More Cognitive Surrender Where It Just Won’t Do.  Last week we considered an essay on AI that used the term “cognitive surrender.”  That sums up the current state of that art and the term should gain a following.  Last week Nature published Is AI ruining our skills?  Early results are in – […]

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Coffee Break: More on American Science, An NIH Grant Long Overdue, An Experimental Model, and Further Thoughts on AI

Part the First: Back to the Past in Science and Medicine.  The future of basic science in the United States looks grim for everyone from the aspiring graduate student to the full professor who has met her potential and has several graduate students, postdocs, and technicians working in her laboratory.  The precipitous and arbitrary Big […]

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A New Cancer Drug and the Nature of Scientific Discovery

Glen Campbell, who was a member of The Wrecking Crew, once remarked that he had worked hard for ten years to become an overnight success in 1967, with thanks to John Hartford.  Without stretching too much, this same trajectory, extended by more than ten years, has been illustrated recently in biomedical research by the case […]

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Coffee Break: American Science in Distress, Technology vs. Community, and the Restaurant Problem Solved

Part the First: The Sabotage of American Science.  For much of the past forty years I have been in the “business” of writing grant proposals and/or doing research that has been publicly funded by the National Institutes of Health and the National Science Foundation.  This includes work supported by the American Cancer Society (ACS) and […]

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Coffee Break: Theology at Work in the World, Eugenics Is Still Undead, Science Is Still Under Attack, and Ultra-Processed Foods in the Dock

Part the First: Pope Leo XIV and the Larger World.  Of the academic historians currently writing for both their colleagues and students and the general reader, Greg Grandin is among the finest.  In The Education of Pope Leo XIV he places the former Father Bob Prevost and current Pope Leo XIV in context of our […]

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A Food Philosophy for Our Time?

It is clear that in much of the so-called developed world, food has largely lost its meaning beyond nourishment.  Julian Baggini has written about this, ten years ago in The Virtues of the Table, which is especially useful in considering how and why we eat.  More recently Baggini has expanded his range in How the […]

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Coffee Break: Ancient Art, the Return of Analog, Science in Distress, and Death Is for Losers

Part the First: Functional Art from the Enigmatic Daunians.  William Morris famously wrote, “Have nothing in your houses that you do not know to be useful or believe to be beautiful.”  Of course, his beauty in response to the immiseration of the working class was for the English rich but nothing is perfect.  Our old […]

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Coffee Break: The Furies are Coming for US

Today’s Coffee Break on a holiday weekend in the US  is the simple recommendation that you go straight to this long essay in Front Porch Republic by W. Aaron Vandiver of Carbondale, Colorado: Trump and the Furies of Empire –– Trump, in his crude way, is forcing us to confront the false stories we have […]

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The One Big Beautiful Bill Act and Medical Education in These United States

On Independence Day of 2025 President Trump signed his One Big Beautiful Bill Act (OBBBA) into law.  Something that has not gotten much attention, so far, are the consequences OBBBA will have on students who must borrow money to attend college/university, graduate school, and/or professional school.  Should American students be forced to go into debt […]

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Coffee Break: Scientists and the Growth Economy, Sternly Worded Letters, Scientist Runs Afoul of RFKJr, Timothy Snyder with the Editor of Science, and Wither Food

Dear gentle readers: Apologies for a somewhat ragged Coffee Break today.  Traveling in Scotland and time has been taken up with details (all good) along with a few unexpected disconnects (as in stuff happens). Part the First: Scientists to the Rescue?  Economic growth is not the answer to any of our problems in this finite […]

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Coffee Break: Counterfeit Scientific Papers, Deep Fakes, CDC on the Ropes, MAHA, and Hope from the Middle of the Country

Part the First: Paper Mills and the Corruption of Research.  No not Hammermill.  I don’t think I have actually known of someone buying a “scholarly” paper for publication, and I remember reading (a few paragraphs) only a few that seemed to be purpose built.  But following up on The Credibility Crisis in Science from earlier […]

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