Author Archives: KLG

Coffee Break: CDC and Acceleration of the Doom Loop

Part the First and Only on this Friday Afternoon: One More Revolution of the Accelerating Doom Loop of Science. The following is an update to our previous discussion earlier this week.  As everyone should know by now, the Secretary of Health and Human Services has fired the Director of the Centers for Disease Control, Dr. […]

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Is American Science Stuck in a Doom Loop?

The American scientific community is in a difficult place.  I started my first job in an academic research laboratory (funded by the Energy Research and Development Administration and the National Science Foundation) in 1975, which somehow was fifty years ago when I was the youngest person in the laboratory instead of the oldest.  I have […]

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Coffee Break: Beware the Jargon, Chocolate(!), Arsenic Life Final Update, Death Becomes Us, and the Scopes Trial,

Part the First: Beware Scientific Jargon.  But everyone here already knows that.  Nevertheless, this is a perpetual challenge for every scientist and other scholar who wants to be understood by our fellow citizens without “dumbing it down.”  Scientific jargon can be ‘satisfying’ — but misleading.  Jargon works especially well for those of my tribe who […]

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Coffee Break: AI Deskills Healthcare, mRNA on the Block, Three Hominins Living Together, the Workweek, and a College Essay Worth Reading

Part the First: AI and Deskilling in Healthcare.  Yes, it does happen as described in the news article As AI spreads through health care, is the technology degrading providers’ skills? (New study suggests that, after having a specialized tool taken away, clinicians were less proficient at colonoscopies): The AI colonoscopy tool rolled out across four […]

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Science Fiction Science and Artificial Intelligence in Our Future

The 7 August 2025 issue of Nature included an interesting article on The Science Fiction Science Method (paywall) by Iyad Rahwan, Azim Shariff, and Jean-François Bonnefon.  The scientific method is difficult enough to understand these days, especially regarding previously important but mundane scientific advances such as vaccines.  The Science Fiction Science (SFS) Method is likely […]

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Coffee Break: Biotech vs. Science, NIH Under New Management, More on Malaria, Dreams of De-Extinction, and an Aside on the State of America

Part the First: Is This How to Do Science? San Diego, with the University of California-San Diego and the Scripps Research Institute leading the way, has been a Biotech/Little Pharma hotspot since the beginning, a strong third behind Boston and the Bay Area. Ups and downs are common, but in the current climate it is […]

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Coffee Break: COVID-19 and Cancer, NIH Weaponized Against the People, Consciousness, AI and the Internet, and Famine

Part the First: How Do You Awaken Sleeping Cancer Cells.  Short answer: Inflammation.  Speaking from experience, anyone who have ever been treated successfully for cancer never fully relaxes after his or her tumor or condition is resolved.  Formerly metastatic cells can remain dormant for a long time.  Recent research has shown how they are reawakened. […]

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Funding the Fundamentals of Biomedical Science: The National Institutes of Health in 2025 and Beyond

In the United States, the aim of the Current Administration is to support something called “gold-standard science.”  Their clear implication is that American scientists have been publishing something less than the gold standard – perhaps silver or bronze, or maybe even brass, when gold is the standard of the day (here and here).  We have […]

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Coffee Break: Garden of Healing, Good News on PEPFAR, Life in Biotech, and Our American Israel

Part the First: Pharmacopeia.  Who doesn’t love a garden?  It sometimes seems that all drugs come from plants, initially.  My first biology teachers claimed they were taught that bacteria were plants back when life was either animal or plant.  Garden of Healing is a bit long but very interesting.  It is also a break from […]

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Hayek’s Bastards and the Rise of Neoliberalism

The Neoliberal turn of late capitalism [1] rules our world.  Quinn Slobodian has become the voice of our time in explaining how this has happened and why.  In Globalists The End of Empire and the Birth of Neoliberalism (2020), he described, among other things, how the Liberals of Central Europe who became Neoliberals were most […]

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Coffee Break: AI in Healthcare and Science, the Nature of Charisma, and a Cure from a Mouse to a Patient

Part the First: Algorithmic Intelligence in Clinical Medicine. From the article This Ohio health system tested an AI tool to predict sepsis. Here’s how it went.  As the subhead notes: Summa Health’s experience highlights the challenges of AI adoption, especially at community health systems: Across emergency departments around Akron, Ohio, physicians were getting overwhelmed. In […]

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Coffee Break: Ancient Food Facts, Cancer Therapy, the Conscious Brain, and Biohacking with Biotech…Plus Thomas Jefferson

On this Independence Day in one country in North America a few notes on life outside current politics, scientific and otherwise. Part the First: The Archaeology of Food Is Fascinating.  Having read about Roman eating habits over the years I have wondered about two things, fish sauce and the dormouse.  Now we know which fish […]

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Trust in Science, Public Health, and Politics: Lessons from COVID-19

Shortly after COVID-19 was recognized as a worldwide catastrophe, my much better half asked me how long I thought this would this last.  Based on my then 45 years of biomedical research experience I replied, “Three years.”  I was wrong.  That was more than five years ago, when the refrigerated makeshift morgues were parked on […]

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Coffee Break: Funding Medical Education, A Human Ancestor, Tardigrades to the Rescue, Trashing the Earth, Plus MAHA and Measles

Part the First: Financing Professional Education in the United States.  College costs too much in the United States.  Professional School costs way to much.  Up until the present – who knows what will happen next as the broad attacks on American universities continue – graduate education at the PhD level in traditional disciplines in the […]

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